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publication name Ocular Parameter Changes in Pediatric Patients with Nephrotic Syndrome
Authors WESAM E. AFIFI, M.D.*; AHMED A. TABL, M.D.**; MAHMOUD A. ABD EL MOHSEN, M.Sc.*** and MOHAMED S. SLEEM, M.D.
year 2022
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Abstract

Background: Nephrotic syndrome has a relapsing nature that necessitates prolonged use of steroids and other immunosuppressive drugs. Systemic steroid administration is associated with multiple ocular side effects. This study was conducted to report various ocular manifestations in pediatric patients with nephrotic syndrome. Aim Study: The aim of our study is to report various ocular manifestations in children with idiopathic nephroticsyndrome. Patients and Methods: This cross-sectional case control study included 100 cases diagnosed with nephrotic syndrome and 50 healthy controls. All subjects were subjected to detailed history taking, general examination, and laboratory investigations. Also, comprehensive ophthalmological examination (including visual acuity, slit lamp microscopy, intraocular pressure measurement, and fundus examination) were performed. Results: Unaided visual acuity was significantly increased in cases compared to controls, and that was evident in both right and left eyes. IOP was significantly elevated in cases compared to controls (p0.05). Conclusion: There is an increased incidence of ocular complications in pediatric cases with nephrotic syndrome. It is recommended that these cases should have regular ophthalmological examination for early detection of these complications.

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