Background: Nephrotic syndrome has a relapsing nature
that necessitates prolonged use of steroids and other immunosuppressive drugs. Systemic steroid administration is associated with multiple ocular side effects. This study was
conducted to report various ocular manifestations in pediatric
patients with nephrotic syndrome.
Aim Study: The aim of our study is to report various
ocular manifestations in children with idiopathic nephroticsyndrome.
Patients and Methods: This cross-sectional case control
study included 100 cases diagnosed with nephrotic syndrome
and 50 healthy controls. All subjects were subjected to detailed
history taking, general examination, and laboratory investigations. Also, comprehensive ophthalmological examination
(including visual acuity, slit lamp microscopy, intraocular
pressure measurement, and fundus examination) were performed.
Results: Unaided visual acuity was significantly increased
in cases compared to controls, and that was evident in both
right and left eyes. IOP was significantly elevated in cases
compared to controls (p0.05).
Conclusion: There is an increased incidence of ocular
complications in pediatric cases with nephrotic syndrome. It
is recommended that these cases should have regular ophthalmological examination for early detection of these complications.