The present research aimed at investigating the Interaction Effect of Thinking types:( positive thinking type, negative thinking type); Gender factor:( male, female) and Studying Specific factor:( science branch, art branch) on Motivational Regulation Strategies:(motivational regulation strategies related with intra-motivation, motivational regulation strategies related with inter-motivation); among (318) fourth year students in different scientific and literary specializations at the faculty of education, Benha University. To achieve this aim, the researcher used some tools: Arabic Scale for positive thinking (prepared by:Abdel-Sattar Ibrahim, 2008) and motivational regulation strategies scale (prepared by Wolters, 2003, translated by Ezzat Abdel-Hamid, 2007). The research showed that differ in using motivational strategies according to the interaction between :( thinking types 2, gender factor 2 and specific factor 2). The research introduced some recommendations and suggested research and studies on the light of the results of statistical analysis