| publication name | Evaluation of Plasma microRNA-33 in Psoriatic Patients and its correlation with insulin resistance and common carotid artery intima-media wall thickness |
|---|---|
| Authors | Dr. Abd El-Aziz Ibrahim Abd El-Aziz El-Taweel ,Dr. Hanan Hassan Sabry,Dr. Jihan Hassan Sabry Samah Ezzat Ibahim Sherif |
| year | 2019 |
| keywords | Psoriasis, miRNA-33, Insulin resistance, Carotid intima media thickness |
| journal | |
| volume | Not Available |
| issue | Not Available |
| pages | 149 |
| publisher | Not Available |
| Local/International | Local |
| Paper Link | Not Available |
| Full paper | download |
| Supplementary materials | SAMAH EZZAT IBRAHIM SHERIF_09 Chapter II.docx |
Abstract
Psoriatic patients exhibited more atherogenic lipid profile, higher CIMT and HOMA-IR values than healthy individuals. MiR-33 is significantly elevated in plasma of psoriatic patients and is correlated with PASI score. Moreover, MiR-33 is positively correlated with HOMA-IR and CIMT. In conclusion, miRNA-33 can be used as potential biomarker for psoriasis and as a predictor for cardiovascular comorbidity as increased insulin resistance and subclinical atherosclerosis in psoriatic patients.