Staff Members - Benha University
Evaluation of Plasma microRNA-33 in Psoriatic Patients and its correlation with insulin resistance and common carotid artery intima-media wall thickness
• 2019
Publication Information
Authors
Dr. Abd El-Aziz Ibrahim Abd El-Aziz El-Taweel ,Dr. Hanan Hassan Sabry,Dr. Jihan Hassan Sabry Samah Ezzat Ibahim Sherif
Keywords
Psoriasis, miRNA-33, Insulin resistance, Carotid intima media thickness
Journal
Not Available
Publisher
Not Available
Volume
Not Available
Issue
Not Available
Pages
149
publication.type
Local
Paper Link
Not Available
Supplementary Materials
SAMAH EZZAT IBRAHIM SHERIF_09 Chapter II.docx
Abstract
Psoriatic patients exhibited more atherogenic lipid profile, higher CIMT and HOMA-IR values than healthy individuals.
MiR-33 is significantly elevated in plasma of psoriatic patients and is correlated with PASI score.
Moreover, MiR-33 is positively correlated with HOMA-IR and CIMT.
In conclusion, miRNA-33 can be used as potential biomarker for psoriasis and as a predictor for cardiovascular comorbidity as increased insulin resistance and subclinical atherosclerosis in psoriatic patients.
MiR-33 is significantly elevated in plasma of psoriatic patients and is correlated with PASI score.
Moreover, MiR-33 is positively correlated with HOMA-IR and CIMT.
In conclusion, miRNA-33 can be used as potential biomarker for psoriasis and as a predictor for cardiovascular comorbidity as increased insulin resistance and subclinical atherosclerosis in psoriatic patients.