أعضاء هيئة التدريس - جامعة بنها
Evaluation of Plasma microRNA-33 in Psoriatic Patients and its correlation with insulin resistance and common carotid artery intima-media wall thickness
• 2019
معلومات البحث
المؤلفون
Dr. Abd El-Aziz Ibrahim Abd El-Aziz El-Taweel ,Dr. Hanan Hassan Sabry,Dr. Jihan Hassan Sabry Samah Ezzat Ibahim Sherif
الكلمات المفتاحية
Psoriasis, miRNA-33, Insulin resistance, Carotid intima media thickness
المجلة العلمية
Not Available
الناشر
Not Available
المجلد
Not Available
العدد
Not Available
الصفحات
149
publication.type
Local
رابط البحث
Not Available
المواد المرفقة
SAMAH EZZAT IBRAHIM SHERIF_09 Chapter II.docx
الملخص
Psoriatic patients exhibited more atherogenic lipid profile, higher CIMT and HOMA-IR values than healthy individuals.
MiR-33 is significantly elevated in plasma of psoriatic patients and is correlated with PASI score.
Moreover, MiR-33 is positively correlated with HOMA-IR and CIMT.
In conclusion, miRNA-33 can be used as potential biomarker for psoriasis and as a predictor for cardiovascular comorbidity as increased insulin resistance and subclinical atherosclerosis in psoriatic patients.
MiR-33 is significantly elevated in plasma of psoriatic patients and is correlated with PASI score.
Moreover, MiR-33 is positively correlated with HOMA-IR and CIMT.
In conclusion, miRNA-33 can be used as potential biomarker for psoriasis and as a predictor for cardiovascular comorbidity as increased insulin resistance and subclinical atherosclerosis in psoriatic patients.