| publication name | Antigenic relatedness of FMD serotypes O and A local Egyptian isolate with vaccinal strains in the local commercial and imported vaccines. |
|---|---|
| Authors | Gabr. F. El-Bagoury1 , Saad. S.A Sharawi1 , Ehab. M. El-Nahas1 , Darwish. M. Darwish2 , Mohammed. A. Saad.2 |
| year | 2015 |
| keywords | |
| journal | |
| volume | Not Available |
| issue | Not Available |
| pages | Not Available |
| publisher | Not Available |
| Local/International | Local |
| Paper Link | Not Available |
| Full paper | download |
| Supplementary materials | Not Available |
Abstract
Foot-and-mouth disease (FMD) is a highly contagious and economically devastating viral disease of clovenhoofed animals. In Egypt, the local commercial (trivalent O Panasia-2/A Iran-05/ SAT2/EGY-A-2012) and imported (trivalent O Manisa /A Iran-05/ SAT2/EGY-A-2012) inactivated vaccines were used for rapid control of the disease. Our study aimed to determine the antigenic relatedness (R-value) of FMD virus serotypes O and A local Egyptian isolate with vaccinal strains in the local commercial and imported vaccines using serum neutralization test (SNT). At 28th day post vaccination with either local commercial or imported vaccines, the calculated R-values for O/EGY-4-2012 were 0.84 with O Panasia-2 in local commercial vaccine and 0.65 with O Manisa in imported vaccine. A/EGY/1/2012 showed R-value 0.78 and 0.72 with A Iran-05 in local commercial and imported vaccines respectively. In conclusion, FMD virus Egyptian isolates O and A was antigenically similar to that of vaccinal strains in local commercial and imported vaccines, which provide good protection.