Staff Members - Benha University
Antigenic relatedness of FMD serotypes O and A local Egyptian isolate with vaccinal strains in the local commercial and imported vaccines.
• 2015
Publication Information
Authors
Gabr. F. El-Bagoury1
, Saad. S.A Sharawi1
, Ehab. M. El-Nahas1
, Darwish. M. Darwish2
, Mohammed.
A. Saad.2
Keywords
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publication.type
Local
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Supplementary Materials
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Abstract
Foot-and-mouth disease (FMD) is a highly contagious and economically devastating viral disease of clovenhoofed animals. In Egypt, the local commercial (trivalent O Panasia-2/A Iran-05/ SAT2/EGY-A-2012) and
imported (trivalent O Manisa /A Iran-05/ SAT2/EGY-A-2012) inactivated vaccines were used for rapid
control of the disease. Our study aimed to determine the antigenic relatedness (R-value) of FMD virus
serotypes O and A local Egyptian isolate with vaccinal strains in the local commercial and imported vaccines
using serum neutralization test (SNT). At 28th day post vaccination with either local commercial or imported
vaccines, the calculated R-values for O/EGY-4-2012 were 0.84 with O Panasia-2 in local commercial
vaccine and 0.65 with O Manisa in imported vaccine. A/EGY/1/2012 showed R-value 0.78 and 0.72 with
A Iran-05 in local commercial and imported vaccines respectively. In conclusion, FMD virus Egyptian
isolates O and A was antigenically similar to that of vaccinal strains in local commercial and imported
vaccines, which provide good protection.
imported (trivalent O Manisa /A Iran-05/ SAT2/EGY-A-2012) inactivated vaccines were used for rapid
control of the disease. Our study aimed to determine the antigenic relatedness (R-value) of FMD virus
serotypes O and A local Egyptian isolate with vaccinal strains in the local commercial and imported vaccines
using serum neutralization test (SNT). At 28th day post vaccination with either local commercial or imported
vaccines, the calculated R-values for O/EGY-4-2012 were 0.84 with O Panasia-2 in local commercial
vaccine and 0.65 with O Manisa in imported vaccine. A/EGY/1/2012 showed R-value 0.78 and 0.72 with
A Iran-05 in local commercial and imported vaccines respectively. In conclusion, FMD virus Egyptian
isolates O and A was antigenically similar to that of vaccinal strains in local commercial and imported
vaccines, which provide good protection.