Staff Members - Benha University
Serum Level of Growth Arrest–Specific 6 (Gas6)Protein and Genetic Variations in the Gas6 Gene inPatients with Type 2 Diabetes Mellitus
• 2015
Publication Information
Authors
Nehad A Fouad. Sheref M Eltaher, Omminea A Abdullah, Ramy A
Metwally
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publication.type
International
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Abstract
Growth arrest-specific protein 6 (Gas6) belongs to a family of vitamin K-dependent coagulation proteins.
Plasma levels of Gas6 are associated to altered glucose tolerance. This study aimed at determining whether
c.843+7G>A Gas6 polymorphism is associated with the development of type 2 diabetes mellitus. The study
included 05 patients with type 2 diabetes and 40 matched controls. The Gas6 protein was measured in serum
using ELISA and Gas6 gene polymorphism by polymerase chain reaction-Restriction Fragment Length
Polymorphism. The GG genotype was the most prevalent in the diabetic patient. The frequency of A allele in
the diabetic group was lower than the control group (P
Plasma levels of Gas6 are associated to altered glucose tolerance. This study aimed at determining whether
c.843+7G>A Gas6 polymorphism is associated with the development of type 2 diabetes mellitus. The study
included 05 patients with type 2 diabetes and 40 matched controls. The Gas6 protein was measured in serum
using ELISA and Gas6 gene polymorphism by polymerase chain reaction-Restriction Fragment Length
Polymorphism. The GG genotype was the most prevalent in the diabetic patient. The frequency of A allele in
the diabetic group was lower than the control group (P