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publication name Synthesis of 3-(phenoxathiin-2-yl)-2-pyrazoline derivatives as new antibacterial and antifungal agents
Authors Mohamed S. Behalo
year 2010
keywords phenoxathiin; pyrazoline; thiazole; antimicrobial activity
journal Journal of Sulfur Chemistry
volume 31
issue 4
pages 287–297
publisher TTaylor & Francis
Local/International International
Paper Link Not Available
Full paper download
Supplementary materials Not Available
Abstract

A new series of 3-(phenoxathiin-2-yl)-5-aryl-2-pyrazoline derivatives were synthesized from the reaction of 1-(phenoxathiin-2-yl)-3-phenyl/(4-chlorophenyl)propenones 1a and 1b with different nitrogen nucleophiles. The titled compounds were investigated for their antibacterial and antifungal activities and were compared with the standard drugs. Most of the synthesized compounds demonstrated potent to weak antimicrobial activity.

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