أعضاء هيئة التدريس - جامعة بنها
STUDY OF IRON STATUS PARAMETERS AND SERUM ALUMINUM LEVEL IN PATIENTS WITH CHRONIC RENAL FAILURE .EFFECT OF RECOMBINANT HUMAN ERYTHROPOIETN IN AND OTHER MODALITIES OF TREATMENT
BenhaM.J. • 1997
معلومات البحث
المؤلفون
InasEl-ShaarawyMD.MohamedShawkyMD*,SoberAbdEl-RahmanMD,MohamedEl-HendyMDandSherifNigmMD*
الكلمات المفتاحية
Not Available
المجلة العلمية
BenhaM.J.
الناشر
Not Available
المجلد
Vol. 14N02May1997
العدد
Not Available
الصفحات
347-361
publication.type
International
رابط البحث
Not Available
المواد المرفقة
Not Available
الملخص
Thisstudywasconductedonfifiyuremicpatientsunderregularhaemodialysisand10healthycontrolsubjectsinordertostudytheparametersofironstatusandserumaluminuminthesepatients,andtoellucidatetheefiectofdifferentmodalitiesoftreatmentontheanemia,iron
statusparametersandserumaluminum,
Theuremicpatientswereclassifiedintofivegroups,eachincluded10 i
patients:groupIpatientsdidn'treceivetreatment,group11patientswas
givenTHLLEPO.groupIIIpatientswasgivenoraliron,groupIVpatientsreceivedcorrdvinedEPOandiron,whereasgroupVpatientsreceiveddesferroxamine.Thedurationoftreatmentwas6months.Thefollowinginvestigations, were performed before and after treatment: complete
bloodpicture,bloodurea,serumcreatinine,serumferritin,serumiron,total
ironbindingcapacity,ironbindingsaturation,serumaluminumandbone E
marrow(B.M)biopsy.
Ourstudyshowedthatanemiawasauniversalfindinginalluremic
patients60%hadmicrocytichypochromicand40%hadnormocyticnormochromicanemia.
SerumFe,TIBC,IBSandBMironstorageweresignificantlylowin
uremicpatients,whereasserumferritinandserumaluminumlevelswere
significantlyhighinthesepatients.
statusparametersandserumaluminum,
Theuremicpatientswereclassifiedintofivegroups,eachincluded10 i
patients:groupIpatientsdidn'treceivetreatment,group11patientswas
givenTHLLEPO.groupIIIpatientswasgivenoraliron,groupIVpatientsreceivedcorrdvinedEPOandiron,whereasgroupVpatientsreceiveddesferroxamine.Thedurationoftreatmentwas6months.Thefollowinginvestigations, were performed before and after treatment: complete
bloodpicture,bloodurea,serumcreatinine,serumferritin,serumiron,total
ironbindingcapacity,ironbindingsaturation,serumaluminumandbone E
marrow(B.M)biopsy.
Ourstudyshowedthatanemiawasauniversalfindinginalluremic
patients60%hadmicrocytichypochromicand40%hadnormocyticnormochromicanemia.
SerumFe,TIBC,IBSandBMironstorageweresignificantlylowin
uremicpatients,whereasserumferritinandserumaluminumlevelswere
significantlyhighinthesepatients.