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Correlation of IL1, IL6 and TNF alpha in serum and synovial fluid in rheumatoid arthritis patients regarding to activity .

Egyptian Medical Microbiology & Immunology Journal • 1997
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Publication Information
Authors Mohsen Elbaz ,Mosad Morgan ,Mohamed mMowafy ,Ali Foda.
Keywords Not Available
Journal Egyptian Medical Microbiology & Immunology Journal
Publisher Not Available
Volume 10
Issue Not Available
Pages 176-81
publication.type Local
Paper Link Not Available
Supplementary Materials Not Available
Abstract
The level of Il1, Il6 and TNF alpha were estimated in serum and synovial fluid of Rheumatoid arthritis Group 1)and non Rheumatoid arthritis patients (Group2) and from serum only of apparently healthy people (control ). The results show there are differences in the serum level of the three parameters in
The three groups with significant increase in the frist group than the other groups. Also in group 1 there are varation in the concentarion of the different parameters in the synovial fluid according to the severity of the disease comparing to its serum level . conclusion : estimation of of IL1, IL6 and TNF alpha in Synovial fluid more better than serum as a prognostic value in rheumatoid ariritis but if it is not available serum sample could be used for diagnosis of disease activity.