| publication name | HIGH PLASMA MITOCHONDRIAL DNA EARLY IN PREGNANCY IS A RISK FACTOR FOR DEVELOPMENT OF PREECLAMPSIA. |
|---|---|
| Authors | Hany A. El-Kallaf and Adel F. Al-Kholy |
| year | 2019 |
| keywords | Preeclampsia, Primigravida, mitochondrial DNA, Early prediction. |
| journal | |
| volume | Not Available |
| issue | Not Available |
| pages | Not Available |
| publisher | Not Available |
| Local/International | International |
| Paper Link | Not Available |
| Full paper | download |
| Supplementary materials | Not Available |
Abstract
Objectives: Estimation of plasma mitochondrial DNA (mtDNA) levels in primigravida during 1st trimester and evaluation of its relation to development and severity of preeclampsia (PE). Patients & Methods: The study included 44 PE women (PE group) and 10 women free pf PE (Control group). At the 1st visit, all women underwent complete clinical examination and gave fasting blood sample for investigations. All women were asked to attend 4-weekly till delivery for evaluation of PE manifestations including increased systolic (SBP) and diastolic blood pressure (DBP) with proteinuria. SBP ≥160 mmHg and DBP ≥110 with proteinuria >2+ indicates severe PE and early-onset PE was diagnosed if manifestations appeared at