Staff Members - Benha University
HIGH PLASMA MITOCHONDRIAL DNA EARLY IN PREGNANCY IS A RISK FACTOR FOR DEVELOPMENT OF PREECLAMPSIA.
• 2019
Publication Information
Authors
Hany A. El-Kallaf and Adel F. Al-Kholy
Keywords
Preeclampsia, Primigravida, mitochondrial DNA, Early prediction.
Journal
Not Available
Publisher
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Volume
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Issue
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Pages
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publication.type
International
Paper Link
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Supplementary Materials
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Abstract
Objectives: Estimation of plasma mitochondrial DNA (mtDNA) levels in primigravida during 1st trimester and evaluation of its relation to development and severity of preeclampsia (PE).
Patients & Methods: The study included 44 PE women (PE group) and 10 women free pf PE (Control group). At the 1st visit, all women underwent complete clinical examination and gave fasting blood sample for investigations. All women were asked to attend 4-weekly till delivery for evaluation of PE manifestations including increased systolic (SBP) and diastolic blood pressure (DBP) with proteinuria. SBP ≥160 mmHg and DBP ≥110 with proteinuria >2+ indicates severe PE and early-onset PE was diagnosed if manifestations appeared at
Patients & Methods: The study included 44 PE women (PE group) and 10 women free pf PE (Control group). At the 1st visit, all women underwent complete clinical examination and gave fasting blood sample for investigations. All women were asked to attend 4-weekly till delivery for evaluation of PE manifestations including increased systolic (SBP) and diastolic blood pressure (DBP) with proteinuria. SBP ≥160 mmHg and DBP ≥110 with proteinuria >2+ indicates severe PE and early-onset PE was diagnosed if manifestations appeared at