The present study aimed to investigate the influence of antioxidant of potato peel (Solanum tuberosum, L) on lowering blood lipids as a practical solution to improve the nutritional care for hyperlipidemic patients. The chemical composition of potato peel. Forty eight adult male albino rats (Sprague dawley strain) weighing between (170-180/gm). The rats were divided into 6 groups each of 8 rats. The experiment was carried out in two periods one in 3 weeks and the second in 6 weeks. In the first period, the normal (control group) was fed on basal diet, while the other five groups were fed on hyperlipidemic diet. In the second period, one group of the hyperlipidemic rats fed on hyperlipidemic diet and the other fed on with hyperlipidemic diet supplemented with four levels (5, 10, 15 and 20%) potato peel powder.