| publication name | Interplay of host and infectious agents |
|---|---|
| Authors | Eman Abou Ouf, Silke Bechlars, Evelyn Böttger, Birgül Büyükyazici, Imad Faik, Elisandra Grangeiro de Carvalho,Stefanie Meese, Azzaya Oktyabri, Oluyinka Ol Opaleye, Velavan T. P., Jürgen F. J. Kun |
| year | 2010 |
| keywords | |
| journal | |
| volume | Not Available |
| issue | Not Available |
| pages | Not Available |
| publisher | Not Available |
| Local/International | International |
| Paper Link | Not Available |
| Full paper | download |
| Supplementary materials | Not Available |
Abstract
Summary. In this group we would like to answer the question why people show a diff erent response against certain pathogens. In many infections the course of the disease can range from asymptomatic carriage to the severest forms even death. In the past we have analysed candidate genes and their role in the course of malaria and could detect some polymorphisms infl uencing infectious diseases in the genes encoding NOS2, MBL2, IFNa, FCN2, and receptors for IFNg and IFNa. Having worked initially mainly on malaria we broadened our spectrum also to other infectious diseases like hepatitis B, Leprosy, schistosomiasis. Here we give a short overview about ongoing projects. Key words: Malaria, leprosy, HBV, interferon, NK cells, host genetics. Association of regulatory gene polymorphisms