Staff Members - Benha University
Interplay of host and infectious agents
• 2010
Publication Information
Authors
Eman Abou Ouf, Silke Bechlars, Evelyn Böttger, Birgül Büyükyazici, Imad Faik, Elisandra Grangeiro de Carvalho,Stefanie Meese, Azzaya Oktyabri, Oluyinka Ol Opaleye, Velavan T. P., Jürgen F. J. Kun
Keywords
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publication.type
International
Paper Link
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Supplementary Materials
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Abstract
Summary. In this group we would like to answer the question
why people show a diff erent response against certain pathogens.
In many infections the course of the disease can range
from asymptomatic carriage to the severest forms even death.
In the past we have analysed candidate genes and their role in
the course of malaria and could detect some polymorphisms
infl uencing infectious diseases in the genes encoding NOS2,
MBL2, IFNa, FCN2, and receptors for IFNg and IFNa. Having
worked initially mainly on malaria we broadened our spectrum
also to other infectious diseases like hepatitis B, Leprosy,
schistosomiasis. Here we give a short overview about ongoing
projects.
Key words: Malaria, leprosy, HBV, interferon, NK cells, host
genetics.
Association of regulatory gene polymorphisms
why people show a diff erent response against certain pathogens.
In many infections the course of the disease can range
from asymptomatic carriage to the severest forms even death.
In the past we have analysed candidate genes and their role in
the course of malaria and could detect some polymorphisms
infl uencing infectious diseases in the genes encoding NOS2,
MBL2, IFNa, FCN2, and receptors for IFNg and IFNa. Having
worked initially mainly on malaria we broadened our spectrum
also to other infectious diseases like hepatitis B, Leprosy,
schistosomiasis. Here we give a short overview about ongoing
projects.
Key words: Malaria, leprosy, HBV, interferon, NK cells, host
genetics.
Association of regulatory gene polymorphisms