أعضاء هيئة التدريس - جامعة بنها
Significance of Toll-like receptor 4 ( TLR4 )& liver fatty acid- binding protein (L-FABP) expression in Hepatocellular carcinoma: an immunohistochemical study
• 2020
معلومات البحث
المؤلفون
1. Eman Ibrahim Sadik El-Gendy ,2. Prof. Dr. Reda Mohamed Salem El badawy ,3. Prof. Dr. Ranih Zakaria Amer ,4. Prof. Dr. Taghreed Abd Elsamee Abd Elaziz ,5. Prof. Dr. Hala Adel Agina
الكلمات المفتاحية
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المجلة العلمية
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الناشر
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المجلد
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العدد
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الصفحات
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publication.type
Local
رابط البحث
Not Available
المواد المرفقة
Not Available
الملخص
Back ground: Persistent inflammatory conditions can induce tumorigenesis . It is therefore very important to explore the molecular mechanisms involved in progression from chronic hepatitis to cirrhosis to HCC - to identify factors useful for the development of effective therapies that improve patient survival .
Aim of the study : Evaluation of TLR-4 and L-FABP expression in cases of chronic hepatitis, cirrhosis and HCC and correlate them with clinicopathological parameters.
Methods: A retrospective , immunohistochemical study was performed on 50 liver cases;32 cases of HCC, 10 cases of Chronic hepatitis C, and 8 cases of cirrhosis.
Results: There was statistical significant increase in TLR-4 expression in HCC than both chronic liver hepatitis and cirrhosis(P
Aim of the study : Evaluation of TLR-4 and L-FABP expression in cases of chronic hepatitis, cirrhosis and HCC and correlate them with clinicopathological parameters.
Methods: A retrospective , immunohistochemical study was performed on 50 liver cases;32 cases of HCC, 10 cases of Chronic hepatitis C, and 8 cases of cirrhosis.
Results: There was statistical significant increase in TLR-4 expression in HCC than both chronic liver hepatitis and cirrhosis(P