Staff Members - Benha University
Significance of Toll-like receptor 4 ( TLR4 )& liver fatty acid- binding protein (L-FABP) expression in Hepatocellular carcinoma: an immunohistochemical study
• 2020
Publication Information
Authors
1. Eman Ibrahim Sadik El-Gendy ,2. Prof. Dr. Reda Mohamed Salem El badawy ,3. Prof. Dr. Ranih Zakaria Amer ,4. Prof. Dr. Taghreed Abd Elsamee Abd Elaziz ,5. Prof. Dr. Hala Adel Agina
Keywords
Not Available
Journal
Not Available
Publisher
Not Available
Volume
Not Available
Issue
Not Available
Pages
Not Available
publication.type
Local
Paper Link
Not Available
Supplementary Materials
Not Available
Abstract
Back ground: Persistent inflammatory conditions can induce tumorigenesis . It is therefore very important to explore the molecular mechanisms involved in progression from chronic hepatitis to cirrhosis to HCC - to identify factors useful for the development of effective therapies that improve patient survival .
Aim of the study : Evaluation of TLR-4 and L-FABP expression in cases of chronic hepatitis, cirrhosis and HCC and correlate them with clinicopathological parameters.
Methods: A retrospective , immunohistochemical study was performed on 50 liver cases;32 cases of HCC, 10 cases of Chronic hepatitis C, and 8 cases of cirrhosis.
Results: There was statistical significant increase in TLR-4 expression in HCC than both chronic liver hepatitis and cirrhosis(P
Aim of the study : Evaluation of TLR-4 and L-FABP expression in cases of chronic hepatitis, cirrhosis and HCC and correlate them with clinicopathological parameters.
Methods: A retrospective , immunohistochemical study was performed on 50 liver cases;32 cases of HCC, 10 cases of Chronic hepatitis C, and 8 cases of cirrhosis.
Results: There was statistical significant increase in TLR-4 expression in HCC than both chronic liver hepatitis and cirrhosis(P