| publication name | Evaluation of MicroRNA-210 (miR-210) as a Diagnostic and Prognostic Biomarker in Pre-eclampsia Pregnancies |
|---|---|
| Authors | Fetnat M. Tolba a , Adel M. Agha a , Maha Rachwan a , Basma E. Sakr b , Maha A. Abdella b , Amira M. Abdelrahman |
| year | 2020 |
| keywords | |
| journal | |
| volume | Not Available |
| issue | Not Available |
| pages | Not Available |
| publisher | Not Available |
| Local/International | Local |
| Paper Link | Not Available |
| Full paper | download |
| Supplementary materials | Not Available |
Abstract
Objective: This study aims to assess the level of miR-210 in Egyptian women with pre-eclampsia (PE) and to evaluate its role in diagnosis and prognosis of the disease. Subjects and Methods: The study was conducted on 30 pregnant women with PE divided into two groups: group (I): included 15 cases with mild PE and group (II): included 15 cases of severe PE and, 20 healthy pregnant women with matched age and sex were included as control group. All women included in the study were subjected to, history taking full clinical examination, laboratory investigations included (CBC), (PT), (ALT, AST), (urea, creatinine), detection of protein in urine, as well as miRNA-210 gene expression by RTPCR. Results: Patients with PE showed a highly significantly increase in serum miR-210 (P value