Staff Members - Benha University
Evaluation of MicroRNA-210 (miR-210) as a Diagnostic and Prognostic Biomarker in Pre-eclampsia Pregnancies
• 2020
Publication Information
Authors
Fetnat M. Tolba a
, Adel M. Agha a
, Maha Rachwan a
, Basma E. Sakr b
, Maha A. Abdella b
,
Amira M. Abdelrahman
Keywords
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Journal
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Publisher
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Volume
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Issue
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Pages
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publication.type
Local
Paper Link
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Supplementary Materials
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Abstract
Objective: This study aims to assess the level of miR-210 in
Egyptian women with pre-eclampsia (PE) and to evaluate its role
in diagnosis and prognosis of the disease. Subjects and Methods:
The study was conducted on 30 pregnant women with PE divided
into two groups: group (I): included 15 cases with mild PE and
group (II): included 15 cases of severe PE and, 20 healthy
pregnant women with matched age and sex were included as
control group. All women included in the study were subjected to,
history taking full clinical examination, laboratory investigations
included (CBC), (PT), (ALT, AST), (urea, creatinine), detection of
protein in urine, as well as miRNA-210 gene expression by RTPCR. Results: Patients with PE showed a highly significantly
increase in serum miR-210 (P value
Egyptian women with pre-eclampsia (PE) and to evaluate its role
in diagnosis and prognosis of the disease. Subjects and Methods:
The study was conducted on 30 pregnant women with PE divided
into two groups: group (I): included 15 cases with mild PE and
group (II): included 15 cases of severe PE and, 20 healthy
pregnant women with matched age and sex were included as
control group. All women included in the study were subjected to,
history taking full clinical examination, laboratory investigations
included (CBC), (PT), (ALT, AST), (urea, creatinine), detection of
protein in urine, as well as miRNA-210 gene expression by RTPCR. Results: Patients with PE showed a highly significantly
increase in serum miR-210 (P value