أعضاء هيئة التدريس - جامعة بنها
Evaluation of MicroRNA-210 (miR-210) as a Diagnostic and Prognostic Biomarker in Pre-eclampsia Pregnancies
• 2020
معلومات البحث
المؤلفون
Fetnat M. Tolba a
, Adel M. Agha a
, Maha Rachwan a
, Basma E. Sakr b
, Maha A. Abdella b
,
Amira M. Abdelrahman
الكلمات المفتاحية
Not Available
المجلة العلمية
Not Available
الناشر
Not Available
المجلد
Not Available
العدد
Not Available
الصفحات
Not Available
publication.type
Local
رابط البحث
Not Available
المواد المرفقة
Not Available
الملخص
Objective: This study aims to assess the level of miR-210 in
Egyptian women with pre-eclampsia (PE) and to evaluate its role
in diagnosis and prognosis of the disease. Subjects and Methods:
The study was conducted on 30 pregnant women with PE divided
into two groups: group (I): included 15 cases with mild PE and
group (II): included 15 cases of severe PE and, 20 healthy
pregnant women with matched age and sex were included as
control group. All women included in the study were subjected to,
history taking full clinical examination, laboratory investigations
included (CBC), (PT), (ALT, AST), (urea, creatinine), detection of
protein in urine, as well as miRNA-210 gene expression by RTPCR. Results: Patients with PE showed a highly significantly
increase in serum miR-210 (P value
Egyptian women with pre-eclampsia (PE) and to evaluate its role
in diagnosis and prognosis of the disease. Subjects and Methods:
The study was conducted on 30 pregnant women with PE divided
into two groups: group (I): included 15 cases with mild PE and
group (II): included 15 cases of severe PE and, 20 healthy
pregnant women with matched age and sex were included as
control group. All women included in the study were subjected to,
history taking full clinical examination, laboratory investigations
included (CBC), (PT), (ALT, AST), (urea, creatinine), detection of
protein in urine, as well as miRNA-210 gene expression by RTPCR. Results: Patients with PE showed a highly significantly
increase in serum miR-210 (P value