أعضاء هيئة التدريس - جامعة بنها
Significance of Anti-C1q Antibodies in Patients with Systemic Lupus Erythematosus as A Marker of Disease Activity and Lupus Nephritis
THE EGYPTIAN JOURNAL OF IMMUNOLOGY • 2016
معلومات البحث
المؤلفون
Amal F Soliman, Sami EL-Said Egailla, Eman R Abdel Gawad,Amira I Mansour, Tohamy H ElKhouly, Marwa YA Mahgoub
الكلمات المفتاحية
Antic1q, Nephritis, SLE
المجلة العلمية
THE EGYPTIAN JOURNAL OF IMMUNOLOGY
الناشر
Not Available
المجلد
Vol. 23
العدد
(1)
الصفحات
107-116
publication.type
International
رابط البحث
Not Available
المواد المرفقة
Not Available
الملخص
Anti-C1q autoantibodies have been proposed as a useful marker in SLE. This study aimed at measuring
serum levels of anti-C1q antibodies in patients with SLE and investigates correlations of this level with the
histopathological classes of renal biopsies and disease activity. The anti-C1q antibody level was measured
in 30 females SLE patients and 20 controls. The activity of SLE disease was calculated according to the SLE
disease activity index. A renal biopsy from patients with clinical manifestations of renal disease was
obtained. There was a significant increase in the level of anti-C1q antibodies in SLE patients than controls
and in patients with active LN than inactive LN (P
serum levels of anti-C1q antibodies in patients with SLE and investigates correlations of this level with the
histopathological classes of renal biopsies and disease activity. The anti-C1q antibody level was measured
in 30 females SLE patients and 20 controls. The activity of SLE disease was calculated according to the SLE
disease activity index. A renal biopsy from patients with clinical manifestations of renal disease was
obtained. There was a significant increase in the level of anti-C1q antibodies in SLE patients than controls
and in patients with active LN than inactive LN (P