Staff Members - Benha University
Significance of Anti-C1q Antibodies in Patients with Systemic Lupus Erythematosus as A Marker of Disease Activity and Lupus Nephritis
THE EGYPTIAN JOURNAL OF IMMUNOLOGY • 2016
Publication Information
Authors
Amal F Soliman, Sami EL-Said Egailla, Eman R Abdel Gawad,Amira I Mansour, Tohamy H ElKhouly, Marwa YA Mahgoub
Keywords
Antic1q, Nephritis, SLE
Journal
THE EGYPTIAN JOURNAL OF IMMUNOLOGY
Publisher
Not Available
Volume
Vol. 23
Issue
(1)
Pages
107-116
publication.type
International
Paper Link
Not Available
Supplementary Materials
Not Available
Abstract
Anti-C1q autoantibodies have been proposed as a useful marker in SLE. This study aimed at measuring
serum levels of anti-C1q antibodies in patients with SLE and investigates correlations of this level with the
histopathological classes of renal biopsies and disease activity. The anti-C1q antibody level was measured
in 30 females SLE patients and 20 controls. The activity of SLE disease was calculated according to the SLE
disease activity index. A renal biopsy from patients with clinical manifestations of renal disease was
obtained. There was a significant increase in the level of anti-C1q antibodies in SLE patients than controls
and in patients with active LN than inactive LN (P
serum levels of anti-C1q antibodies in patients with SLE and investigates correlations of this level with the
histopathological classes of renal biopsies and disease activity. The anti-C1q antibody level was measured
in 30 females SLE patients and 20 controls. The activity of SLE disease was calculated according to the SLE
disease activity index. A renal biopsy from patients with clinical manifestations of renal disease was
obtained. There was a significant increase in the level of anti-C1q antibodies in SLE patients than controls
and in patients with active LN than inactive LN (P