Staff Members - Benha University
Soluble Receptor for Advanced Glycation End Products: a new biomarker in diagnosis of Diabetic Nephropathy
• 2012
Publication Information
Authors
Hesham A Issa, Osama S Elshaer, Ahmed M Awadallah, Tawfik El-Adl
Keywords
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Journal
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Volume
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Issue
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Pages
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publication.type
International
Paper Link
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Supplementary Materials
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Abstract
Background: Diabetic nephropathy is a clinical syndrome characterized by
persistent albuminuria (> 300 mg/d or> 200 mcg/min). The interaction of advanced glycation
end products with their cellular receptor (RAGE) is implicated in the pathogenesis of diabetic
vascular complications. RAGE has a circulating secretory receptor form, soluble RAGE
(sRAGE), which, by neutralizing the action of advanced glycation end products, might exert a
protective role against the development of cardiovascular disease. Objective: to study the ...
persistent albuminuria (> 300 mg/d or> 200 mcg/min). The interaction of advanced glycation
end products with their cellular receptor (RAGE) is implicated in the pathogenesis of diabetic
vascular complications. RAGE has a circulating secretory receptor form, soluble RAGE
(sRAGE), which, by neutralizing the action of advanced glycation end products, might exert a
protective role against the development of cardiovascular disease. Objective: to study the ...