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Soluble Receptor for Advanced Glycation End Products: a new biomarker in diagnosis of Diabetic Nephropathy

• 2012
العودة
معلومات البحث
المؤلفون Hesham A Issa, Osama S Elshaer, Ahmed M Awadallah, Tawfik El-Adl
الكلمات المفتاحية Not Available
المجلة العلمية Not Available
الناشر Not Available
المجلد Not Available
العدد Not Available
الصفحات Not Available
publication.type International
رابط البحث Not Available
المواد المرفقة Not Available
الملخص
Background: Diabetic nephropathy is a clinical syndrome characterized by
persistent albuminuria (> 300 mg/d or> 200 mcg/min). The interaction of advanced glycation
end products with their cellular receptor (RAGE) is implicated in the pathogenesis of diabetic
vascular complications. RAGE has a circulating secretory receptor form, soluble RAGE
(sRAGE), which, by neutralizing the action of advanced glycation end products, might exert a
protective role against the development of cardiovascular disease. Objective: to study the ...