Staff Members - Benha University
Arginine Dimethylation Products in Pediatric Patients with Chronic Kidney Disea
Annals of Medicine and Surgery • 2016
Publication Information
Authors
Akram E. El-Sadek, MD, Lecturer of pediatrics, Eman G. Behery, MD, Ahmed A.
Azab, MD, Associate Professor of pediatrics, Naglaa M. Kamal, MD, Associate
Professor of pediatrics, Mostafa A. Salama, MD, Associate Professor of pediatrics,
Waleed E. Abdulgh
Keywords
Annals of Medicine and Surgery
Journal
Annals of Medicine and Surgery
Publisher
Not Available
Volume
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Issue
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Pages
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publication.type
International
Paper Link
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Supplementary Materials
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Abstract
Background: arginine and its metabolites have been linked to pediatric chronic kidney disease
(CKD). We aimed to estimate serum levels of argninine (Arg), asymmetric dimethylarginine
(ADMA) and symmetric dimethylarginine (SDMA) in pediatric CKD patients and its relation to
altered kidney function.
Patients and Methods: 132 pediatric patients with CKD and 120 healthy age and sex matched
controls were compared regarding; serum Arg, ADMA and SDMA levels.
Results: In comparison to their values in control subjects, serum Arg levels were significantly
lower; serum ADMA levels were non-significantly higher, but serum SDMA levels were
significantly higher in CKD patients (p values: < 0.000; =0.054;
(CKD). We aimed to estimate serum levels of argninine (Arg), asymmetric dimethylarginine
(ADMA) and symmetric dimethylarginine (SDMA) in pediatric CKD patients and its relation to
altered kidney function.
Patients and Methods: 132 pediatric patients with CKD and 120 healthy age and sex matched
controls were compared regarding; serum Arg, ADMA and SDMA levels.
Results: In comparison to their values in control subjects, serum Arg levels were significantly
lower; serum ADMA levels were non-significantly higher, but serum SDMA levels were
significantly higher in CKD patients (p values: < 0.000; =0.054;