Banner

Arginine Dimethylation Products in Pediatric Patients with Chronic Kidney Disea

Annals of Medicine and Surgery • 2016
العودة
معلومات البحث
المؤلفون Akram E. El-Sadek, MD, Lecturer of pediatrics, Eman G. Behery, MD, Ahmed A. Azab, MD, Associate Professor of pediatrics, Naglaa M. Kamal, MD, Associate Professor of pediatrics, Mostafa A. Salama, MD, Associate Professor of pediatrics, Waleed E. Abdulgh
الكلمات المفتاحية Annals of Medicine and Surgery
المجلة العلمية Annals of Medicine and Surgery
الناشر Not Available
المجلد Not Available
العدد Not Available
الصفحات Not Available
publication.type International
رابط البحث Not Available
المواد المرفقة Not Available
الملخص
Background: arginine and its metabolites have been linked to pediatric chronic kidney disease
(CKD). We aimed to estimate serum levels of argninine (Arg), asymmetric dimethylarginine
(ADMA) and symmetric dimethylarginine (SDMA) in pediatric CKD patients and its relation to
altered kidney function.
Patients and Methods: 132 pediatric patients with CKD and 120 healthy age and sex matched
controls were compared regarding; serum Arg, ADMA and SDMA levels.
Results: In comparison to their values in control subjects, serum Arg levels were significantly
lower; serum ADMA levels were non-significantly higher, but serum SDMA levels were
significantly higher in CKD patients (p values: < 0.000; =0.054;