Arginine Dimethylation Products in Pediatric Patients with Chronic Kidney Disea
Annals of Medicine and Surgery • 2016
معلومات البحث
المؤلفون
Akram E. El-Sadek, MD, Lecturer of pediatrics, Eman G. Behery, MD, Ahmed A.
Azab, MD, Associate Professor of pediatrics, Naglaa M. Kamal, MD, Associate
Professor of pediatrics, Mostafa A. Salama, MD, Associate Professor of pediatrics,
Waleed E. Abdulgh
الكلمات المفتاحية
Annals of Medicine and Surgery
المجلة العلمية
Annals of Medicine and Surgery
الناشر
Not Available
المجلد
Not Available
العدد
Not Available
الصفحات
Not Available
publication.type
International
رابط البحث
Not Available
المواد المرفقة
Not Available
الملخص
Background: arginine and its metabolites have been linked to pediatric chronic kidney disease
(CKD). We aimed to estimate serum levels of argninine (Arg), asymmetric dimethylarginine
(ADMA) and symmetric dimethylarginine (SDMA) in pediatric CKD patients and its relation to
altered kidney function.
Patients and Methods: 132 pediatric patients with CKD and 120 healthy age and sex matched
controls were compared regarding; serum Arg, ADMA and SDMA levels.
Results: In comparison to their values in control subjects, serum Arg levels were significantly
lower; serum ADMA levels were non-significantly higher, but serum SDMA levels were
significantly higher in CKD patients (p values: < 0.000; =0.054;
(CKD). We aimed to estimate serum levels of argninine (Arg), asymmetric dimethylarginine
(ADMA) and symmetric dimethylarginine (SDMA) in pediatric CKD patients and its relation to
altered kidney function.
Patients and Methods: 132 pediatric patients with CKD and 120 healthy age and sex matched
controls were compared regarding; serum Arg, ADMA and SDMA levels.
Results: In comparison to their values in control subjects, serum Arg levels were significantly
lower; serum ADMA levels were non-significantly higher, but serum SDMA levels were
significantly higher in CKD patients (p values: < 0.000; =0.054;
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