| publication name | Novel Fluorescent Aminoxy Acids and Aminoxy Hybrid Peptides SYNTHESIS 2011, No. 1, pp 0083–0090 |
|---|---|
| Authors | Alan R. Katritzky, Abdelmotaal Abdelmajeid, Srinivasa R. Tala, M. S. Amine, Peter J. Steel |
| year | 2011 |
| keywords | fluorescence - acylations - amino acids - aminoxy acids – peptides |
| journal | Synthesis |
| volume | No. 1 |
| issue | Not Available |
| pages | 83-90 |
| publisher | © Georg Thieme Verlag Stuttgart ˙ New York |
| Local/International | International |
| Paper Link | https://experts.umn.edu/en/publications/novel-fluorescent-aminoxy-acids-and-aminoxy-hybrid-peptides(2c550c90-be48-4a56-b774-49ee6c0d04a7).html |
| Full paper | download |
| Supplementary materials | Not Available |
Abstract
a-Aminoxy acid conjugates and hybrid a-aminoxy dipeptide conjugates showing blue to green fluorescence (with quantum yields 0.23–0.71) were synthesized (75–92% yield) from N-Acylbenzotriazoles. 7-Methoxycoumarin derivatives were obtained(quantum yields j 0.35–0.71) that could be suitable for peptide assays. The wavelengths of the absorption maxima (lAbs) and the fluorescence emission maxima (lEm) and the quantum yields (j) of some coumarin-3-ylcarbonyl aminoxy acid conjugates were comparable to those of the analogous amino acid derivatives.