أعضاء هيئة التدريس - جامعة بنها
Novel Fluorescent Aminoxy Acids and Aminoxy Hybrid Peptides SYNTHESIS 2011, No. 1, pp 0083–0090
Synthesis • 2011
معلومات البحث
المؤلفون
Alan R. Katritzky, Abdelmotaal Abdelmajeid, Srinivasa R. Tala, M. S. Amine, Peter J. Steel
الكلمات المفتاحية
fluorescence - acylations - amino acids - aminoxy acids – peptides
المجلة العلمية
Synthesis
الناشر
© Georg Thieme Verlag Stuttgart ˙ New York
المجلد
No. 1
العدد
Not Available
الصفحات
83-90
publication.type
International
رابط البحث
Open Link
المواد المرفقة
Not Available
الملخص
a-Aminoxy acid conjugates and hybrid a-aminoxy
dipeptide conjugates showing blue to green fluorescence (with quantum yields 0.23–0.71) were synthesized (75–92% yield) from N-Acylbenzotriazoles. 7-Methoxycoumarin derivatives were obtained(quantum yields j 0.35–0.71) that could be suitable for peptide
assays. The wavelengths of the absorption maxima (lAbs) and
the fluorescence emission maxima (lEm) and the quantum yields (j)
of some coumarin-3-ylcarbonyl aminoxy acid conjugates were
comparable to those of the analogous amino acid derivatives.
dipeptide conjugates showing blue to green fluorescence (with quantum yields 0.23–0.71) were synthesized (75–92% yield) from N-Acylbenzotriazoles. 7-Methoxycoumarin derivatives were obtained(quantum yields j 0.35–0.71) that could be suitable for peptide
assays. The wavelengths of the absorption maxima (lAbs) and
the fluorescence emission maxima (lEm) and the quantum yields (j)
of some coumarin-3-ylcarbonyl aminoxy acid conjugates were
comparable to those of the analogous amino acid derivatives.