| publication name | Significance of Expression of IMP3, PPARG & PD-L1 in Urothelial Carcinoma (Immunohistochemical Study) |
|---|---|
| Authors | Rasha M. El Sawi a, Ebtehal Abdel Aal a , Amr El-Sebaaie b , Nehal Zafer a, Hala Agina a |
| year | 2020 |
| keywords | Urothelial carcinoma, IMP3, PPARG, PD-L1. |
| journal | |
| volume | Not Available |
| issue | Not Available |
| pages | Not Available |
| publisher | Not Available |
| Local/International | Local |
| Paper Link | Not Available |
| Full paper | download |
| Supplementary materials | Not Available |
Abstract
Background: IMP3, PPARG and PD-L1 have been implicated in tumorigenesis and progression in many cancers, but their significance in urothelial carcinoma remains unclear. Aim: The aim of this study is to assess the possible significance of IMP3, PPARG and PD-L1 in urothelial bladder carcinoma and determine the relation between their expressions and different clinicopathological (tumor size, grade, histological variant, muscle invasion, lymphovascular invasion and pathologic T stage) and molecular variables. Methods: This study aimed to evaluate immunohistochemical expression of IMP3, PPARG and PD-L1 and correlate them with clinicopathological and molecular variables. Results: IMP3 was significantly correlated to muscle invasion (P