Staff Members - Benha University
Significance of Expression of IMP3, PPARG & PD-L1 in Urothelial Carcinoma (Immunohistochemical Study)
• 2020
Publication Information
Authors
Rasha M. El Sawi a, Ebtehal Abdel Aal a , Amr El-Sebaaie b , Nehal Zafer a, Hala Agina a
Keywords
Urothelial carcinoma, IMP3, PPARG, PD-L1.
Journal
Not Available
Publisher
Not Available
Volume
Not Available
Issue
Not Available
Pages
Not Available
publication.type
Local
Paper Link
Not Available
Supplementary Materials
Not Available
Abstract
Background: IMP3, PPARG and PD-L1 have been implicated in tumorigenesis and progression in many cancers, but their significance in urothelial carcinoma remains unclear. Aim: The aim of this study is to assess the possible significance of IMP3, PPARG and PD-L1 in urothelial bladder carcinoma and determine the relation between their expressions and different clinicopathological (tumor size, grade, histological variant, muscle invasion, lymphovascular invasion and pathologic T stage) and molecular variables. Methods: This study aimed to evaluate immunohistochemical expression of IMP3, PPARG and PD-L1 and correlate them with clinicopathological and molecular variables. Results: IMP3 was significantly correlated to muscle invasion (P