This study was conducted to evaluate the effects of dietary supplementation of antibiotic, oregano essential oil and garlic powder as feed additives in quail diets on the productive performance. A total number of 540 unsexed one week old Japanese chicks were randomly distributed into nine experimental treatments, each of 60 birds (3 replicates of 20 birds each). Chicks of the 1st experimental group were fed on basal diet (without additives) and considered as a control group. Chicks of the 2nd and 3rd experimental groups were fed on basal diets supplemented with Oxytetracycline at levels of 0.5 and 1.0 g/kg diet, respectively. Chicks of the 4th, 5th and 6th groups were fed on basal diets supplemented with oregano essential oil (OEO) at levels of 0.5, 1.0 and 1.5 g/kg diet, respectively. While, chicks of the 7th, 8th and 9th groups were fed basal diets supplemented with garlic powder (GP) at levels of 0.1, 0.2 and 0.3 g/kg diet, respectively. The results showed that highly significant differences (p