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Effect of Gentamicin on urinary Calcium Creatinine Ratio and Serum Calcium in Neonates

• 2022
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Publication Information
Authors y Marwa T. Zaghloul3 , Asmaa A. EL Fallah2 , A
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publication.type Local
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Abstract
Introduction: Gentamicin was associated with an apparent increase in the number of neonates with
symptoms of hypocalcemia, including seizures.
Aim of the study: This study aimed to assess the effect of gentamicin on calcium /creatinine ratio in
urine and serum calcium in neonates.
Methods: This case-control study included 100 children, divided into two groups. Group I: Fifty
neonates received gentamicin. Group II: Fifty neonates did not receive antibiotics at all (control group),
Serum calcium and urinary calcium/creatinine ratio, were done at 1st day of admission, and at day 3 and
6 of aminoglycosides therapy.
Results: On admission, serum calcium showed a non-significant difference between both groups, Pvalue was 0.453. On the 3rd day, serum calcium was significantly lower in cases compared to controls
with P-value was