This study sought to determine the prevalence and predictors of peripheral neuropathy in children with chronic kidney disease (CKD). is to evaluate the clinical and electrophysiological abnormalities in upper limbs of children on hemodialysis treatment at dialysis unit at Benha university Hospital. Our study was acase control study (descripitive and comparative). The study will be conducted on 60 children The CKD group consisted of 30 patients, all of them complained from end stage irreversible renal failure, 20 on hemodialysis (GFR