Staff Members - Benha University
SENSITIVITY AND SPECIFICITY OF MYOGLOBIN IN EARLY DIAGNOSIS OF ACUTE MYOCARDIAL INFARCTION
• 1993
Publication Information
Authors
Tawheed M. Mowafi , Nabil A. Khattab ,Alaa Ibrahim , Yahia Saddik , Ahmed Saleh ,Fawzy M. Khalil , Maha Youssef *
Keywords
Not Available
Journal
Not Available
Publisher
Not Available
Volume
Not Available
Issue
Not Available
Pages
Not Available
publication.type
International
Paper Link
Not Available
Supplementary Materials
Not Available
Abstract
This work was carried out on 24 patients suffering from acute chest
pain suspicious of acute myocardial infarction ( AMI ) and 10 well
matched normal controls . Patients and controls had undergone electro- cardiographic monitoring ( ECG ) , determination of serum creatine
phosphokinace ( CPK ) and serum myoglobin by turbidimetric immunoassay.
Out of these 24 patients 9 proved to have unstable angina and
15 had AM! . Eleven patients were admitted within 24 hours and
13 within 6 hours from the onset of chest pain. Out of these 13 patients
only 9 had AM! . Sensitivity of myoglobin , CPK and ECG
in all patients with AM! was 86.8% , 60% and 66.6% respectively.
The sensitivity of myoglobin and CPK in AMI patients admitted within
6 hours was 88.8% and 33.33% , respectively . The specificity
for myoglobin , CPK and ECG in all AMI patients was 100% .Therefore
serum myzolobin assay by immunoturbidmetric method can be
considered as a sensitive and specific test to diagnose AMI in the first
few hours and also to identify those patients without definite ECG
changes.
pain suspicious of acute myocardial infarction ( AMI ) and 10 well
matched normal controls . Patients and controls had undergone electro- cardiographic monitoring ( ECG ) , determination of serum creatine
phosphokinace ( CPK ) and serum myoglobin by turbidimetric immunoassay.
Out of these 24 patients 9 proved to have unstable angina and
15 had AM! . Eleven patients were admitted within 24 hours and
13 within 6 hours from the onset of chest pain. Out of these 13 patients
only 9 had AM! . Sensitivity of myoglobin , CPK and ECG
in all patients with AM! was 86.8% , 60% and 66.6% respectively.
The sensitivity of myoglobin and CPK in AMI patients admitted within
6 hours was 88.8% and 33.33% , respectively . The specificity
for myoglobin , CPK and ECG in all AMI patients was 100% .Therefore
serum myzolobin assay by immunoturbidmetric method can be
considered as a sensitive and specific test to diagnose AMI in the first
few hours and also to identify those patients without definite ECG
changes.