Staff Members - Benha University
Study of the Helicobacter pylori infection in chronic obstructive pulmonary disease
Egyptian Journal of Chest Diseases and Tuberculosis • 2016
Publication Information
Authors
Shereef A. Eisa a
, Gehan F. Almehy a
, Hisham A. Eisa b
, Maha Z. Omar
c
,
Tarek S. Essawy a
, Amal A. Abou Elnass
a,
Keywords
H. pylori;
COPD;
CagA;
IgG
Journal
Egyptian Journal of Chest Diseases and Tuberculosis
Publisher
Not Available
Volume
65
Issue
Not Available
Pages
567-571
publication.type
International
Paper Link
Not Available
Supplementary Materials
Not Available
Abstract
Abstract Background: COPD may be associated with other systemic diseases including cardiovas-
cular diseases, diabetes, osteoporosis and peptic ulceration and Helicobacter pylori infection seems
to be the main cause of PUD.
Aims: The aim of this work is to study the association of H. pylori infection in chronic obstruc-
tive pulmonary disease (COPD).
Subject and methods: This study was performed on 80 subjects. They were classified into two
groups: Group I: 65 COPD patients. Group II: 20 healthy control subjects. COPD was diagnosed
according to the Global Initiative for chronic obstructive pulmonary disease admitted at chest
department of Benha University Hospital.
Results: It shows that seropositivity of anti-H. pylori IgG and anti-CagA IgG was higher in
COPD patients than in controls with a highly statistically significant difference (p =0.009 and
0.047 respectively). Also the IgG level of H. pylori positive cases and CagA positive cases was higher
in the COPD group than in the control group with a highly statistically significant difference
(p= 0.027 and 0.0001 respectively).
Conclusion: The present study suggests that patients with COPD have an increased seropreva-
lence of Hp infection
cular diseases, diabetes, osteoporosis and peptic ulceration and Helicobacter pylori infection seems
to be the main cause of PUD.
Aims: The aim of this work is to study the association of H. pylori infection in chronic obstruc-
tive pulmonary disease (COPD).
Subject and methods: This study was performed on 80 subjects. They were classified into two
groups: Group I: 65 COPD patients. Group II: 20 healthy control subjects. COPD was diagnosed
according to the Global Initiative for chronic obstructive pulmonary disease admitted at chest
department of Benha University Hospital.
Results: It shows that seropositivity of anti-H. pylori IgG and anti-CagA IgG was higher in
COPD patients than in controls with a highly statistically significant difference (p =0.009 and
0.047 respectively). Also the IgG level of H. pylori positive cases and CagA positive cases was higher
in the COPD group than in the control group with a highly statistically significant difference
(p= 0.027 and 0.0001 respectively).
Conclusion: The present study suggests that patients with COPD have an increased seropreva-
lence of Hp infection