THE PRENATAL AND POSTNATAL EFFECTS OF NICOTINE ON THE HEART AND GREAT VESSELS OF ALBINO RATS AND THE POSSIBLE PROTECTIVE EFFECT OF ASCORBIC ACID (VITAMIN C) ( A LIGHT & ELECTRON MICROSCOPIC STUDY )
• 2018
Publication Information
Authors
Marim Fayz Abdo, Talaat Mustafa Mohamed, Omar Abd El Aziz Allam, ALI Mohamed Ali, Osama Fouad Ahmad.
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publication.type
Local
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Abstract
Nicotine tartrate affects the heart and aortic wall of the developing
rats , during gestation and postnatal periods .
Therefore, exposure to inhaled nicotine tartrate ,either by active or
passive smoking ,must be restricted , especially during pregnancy and
lactation .In addition , increasing awareness of its hazards is
recommended .
Vitamin C is a known chelating agent with non-enzymatic
antioxidant features , was widely reported to have the ability to protect
cells from oxidative stress in nicotine-exposed rats .
So , administration of combined nicotine and ascorbic acid ,
minimize the harmfull effect of nicotine tartrate on developing heart
&aorta .
.
161
rats , during gestation and postnatal periods .
Therefore, exposure to inhaled nicotine tartrate ,either by active or
passive smoking ,must be restricted , especially during pregnancy and
lactation .In addition , increasing awareness of its hazards is
recommended .
Vitamin C is a known chelating agent with non-enzymatic
antioxidant features , was widely reported to have the ability to protect
cells from oxidative stress in nicotine-exposed rats .
So , administration of combined nicotine and ascorbic acid ,
minimize the harmfull effect of nicotine tartrate on developing heart
&aorta .
.
161
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