Staff Members - Benha University
Predictive value of IL-35 and IL-17 in diagnosis of childhood asthma
• 2017
Publication Information
Authors
Amira Ibrahim Mansour, Eman Rateb Abd Almonaem, Ola Galal Behairy &
Tahany Mahmoud Gouda
Keywords
Asthma; cytokines; ELISA;
eosinophils; IgE
Journal
Not Available
Publisher
Not Available
Volume
Not Available
Issue
Not Available
Pages
Not Available
publication.type
International
Paper Link
Not Available
Supplementary Materials
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Abstract
This study aimed to evaluate the correlation between serum levels of IL-17 and IL-35 and the presence
and severity of childhood asthma. The study was performed on 60 diagnosed asthmatic children, who
were further classified into four groups according to the Global Initiative for Asthma Guidelines for
Asthma Severity and Control (GINA) 2016, plus 30 age- and sex-matched apparently healthy children.
All participants were subjected to full medical history, clinical examination, pulmonary function tests
and laboratory evaluation in the form of complete blood count (CBC), serum total IgE, IL-17 and IL-35
by ELISA. Our results revealed that eosinophils count, IgE and IL-17 were significantly higher in the
asthmatic group than the control group (p
and severity of childhood asthma. The study was performed on 60 diagnosed asthmatic children, who
were further classified into four groups according to the Global Initiative for Asthma Guidelines for
Asthma Severity and Control (GINA) 2016, plus 30 age- and sex-matched apparently healthy children.
All participants were subjected to full medical history, clinical examination, pulmonary function tests
and laboratory evaluation in the form of complete blood count (CBC), serum total IgE, IL-17 and IL-35
by ELISA. Our results revealed that eosinophils count, IgE and IL-17 were significantly higher in the
asthmatic group than the control group (p