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Real-Life International Normalized Ratio Profile in Patients with Non-Valvular Atrial Fibrillation Prescribed Vitamin K Antagonist

Rational Pharmacotherapy in Cardiology • 2020
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Publication Information
Authors Shereen Ibrahim Farag, Osama Sanad Arafa, Amal Abou Elfadl Hassan, Haidy Magdy Mashhour, Ahmed Mahmoud Bendary
Keywords vitamin K antagonists, international normalized ratio, coagulation
Journal Rational Pharmacotherapy in Cardiology
Publisher Not Available
Volume 4
Issue Not Available
Pages 522-527
publication.type International
Paper Link Not Available
Supplementary Materials Not Available
Abstract
Coagulation status with vitamin K antagonists (VKAs) needs to be monitored carefully to ensure maximal efficacy with minimal complication rates.
Aim. To study the international normalized ratio (INR) values in patients on VKAs in selected area, find out which patient characteristics that is associated with good INR control and calculation of the time in the therapeutic range (TTR) according to the number of INR/Patient.
Material and methods. A total of 200 patients with non-valvular atrial fibrillation prescribed vitamin K antagonist as anticoagulant were evaluated. They were divided into two groups: group I with TTR≥65% (n=93) and group II with TTR