Staff Members - Benha University
Biochemical alterations of Chitosan on Liver function tests and Immunoglobulin in Experimental induced Non Alcoholic Fatty Liver Disease in Rats
Intternattiionall Journall of Pharma Sciiences • 2017
Publication Information
Authors
Omayma.A.Ragab Abou Zaid*, Omnia M. AbdEl-hamid and Shimaa Ahmed El-Refaey Atwa
Keywords
Not Available
Journal
Intternattiionall Journall of Pharma Sciiences
Publisher
Not Available
Volume
7,
Issue
3
Pages
1794-1798
publication.type
Local
Paper Link
Not Available
Supplementary Materials
Not Available
Abstract
The main objective of this study to investigate the alterations of chitosan on Hepatic function tests and
Immunoglobulin in Experimental induced Nonalcoholic fatty liver disease [NAFLD] in rats. Thirty male albino rats
were divided into three groups [10 rats each]. The first group fed a normal diet and represents the control group.
The second group [NAFLD] fed normal diet enriched with1% cholesterol and 2% coconut oil and act as positive
control [+ve control]. The third group fed on normal diet enriched with1% cholesterol and 2% coconut oil and
chitosan to the basal diet at a dose 5%. Samples collected after 2,4and6 weeks after induction from treatment
.serum was used for estimation of Liver Function Tests as Serum Aspartate aminotransferase [AST], Alanine
aminotransferase [ALT], Gammaglutamyltransferase [GGT] and Immunoglobulins as Serum ImmunoglobulinA
[IgA], Immunoglobulin G [IgG]. Our Results revealed a significantly increase in serum AST, ALT, GGT, Serum IgA, IgG
were significantly increase was observed. The behavioral biochemical results indicated treatment with chitosan
showed significant changes and improves these parameter
Immunoglobulin in Experimental induced Nonalcoholic fatty liver disease [NAFLD] in rats. Thirty male albino rats
were divided into three groups [10 rats each]. The first group fed a normal diet and represents the control group.
The second group [NAFLD] fed normal diet enriched with1% cholesterol and 2% coconut oil and act as positive
control [+ve control]. The third group fed on normal diet enriched with1% cholesterol and 2% coconut oil and
chitosan to the basal diet at a dose 5%. Samples collected after 2,4and6 weeks after induction from treatment
.serum was used for estimation of Liver Function Tests as Serum Aspartate aminotransferase [AST], Alanine
aminotransferase [ALT], Gammaglutamyltransferase [GGT] and Immunoglobulins as Serum ImmunoglobulinA
[IgA], Immunoglobulin G [IgG]. Our Results revealed a significantly increase in serum AST, ALT, GGT, Serum IgA, IgG
were significantly increase was observed. The behavioral biochemical results indicated treatment with chitosan
showed significant changes and improves these parameter