Staff Members - Benha University
Synthesis of Chondroitin Sulfate A Bearing Syndecan-1 Glycopeptide
Organic Letters • 2017
Publication Information
Authors
Sherif Ramadan, Weizhun Yang, Zeren Zhang, and Xuefei Huang
Keywords
Not Available
Journal
Organic Letters
Publisher
American Chemical Society
Volume
19
Issue
18
Pages
4838-4841
publication.type
International
Paper Link
Open Link
Supplementary Materials
Not Available
Abstract
Syndecan-1 chondroitin sulfate glycopeptide was synthesized for the first time using the cassette approach. The sequence of glycosylation to form the octasaccharide serine cassette was critical. The glycopeptide was successfully assembled via a 2+ (3 + 3) glycosylation strategy followed by peptide chain elongation.