| publication name | Synthesis of Chondroitin Sulfate A Bearing Syndecan-1 Glycopeptide |
|---|---|
| Authors | Sherif Ramadan, Weizhun Yang, Zeren Zhang, and Xuefei Huang |
| year | 2017 |
| keywords | |
| journal | Organic Letters |
| volume | 19 |
| issue | 18 |
| pages | 4838-4841 |
| publisher | American Chemical Society |
| Local/International | International |
| Paper Link | https://pubs.acs.org/doi/abs/10.1021/acs.orglett.7b02271 |
| Full paper | download |
| Supplementary materials | Not Available |
Abstract
Syndecan-1 chondroitin sulfate glycopeptide was synthesized for the first time using the cassette approach. The sequence of glycosylation to form the octasaccharide serine cassette was critical. The glycopeptide was successfully assembled via a 2+ (3 + 3) glycosylation strategy followed by peptide chain elongation.