Clinical Characteristics and Short-Term Outcomes of Patients Presenting with Acute Myocardial Infarction having Multi-vessel disease - A Single Middle- eastern Tertiary-Care Center Experience
Indian Heart Journal • 2021
Publication Information
Authors
Sheeren Khaled a, b, *, Najeeb Jaha b, Ghada Shalaby b, c
Keywords
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Journal
Indian Heart Journal
Publisher
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Volume
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Issue
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Pages
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publication.type
International
Paper Link
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Supplementary Materials
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Abstract
Objective: Patients with multi-vessel coronary artery disease (MVD) compared to single-vessel coronary
artery disease (CAD) have more comorbidities and poor in-hospital outcomes. We aim to analyze MVDAMI
patients regarding clinical data and short-term outcomes.
Methods: This is a retrospective analysis of the prospectively collected data registry, a single-center study
reviewing the clinical details and hospital outcome measures of AMI patients referred to our center for
early revascularization from 2016 to 2019.
Result: Out of 3041 patients presented with AMI, 491 (16%) had MVD on coronary angiogram. MVD-AMI
patients were older, had a higher prevalence of DM, HTN, and prior history of ischemic heart disease
compared to the non- MVD -AMI group (p < 0.001 for all). However, they presented more with nonanterior
myocardial infarction, showed higher rates of post-myocardial infarction LV dysfunction, and
mortality (p < 0.001). Older MVD-AMI patients showed higher rates of in-hospital morbidities and
mortality compared to younger ones (p < 0.001). MVD- AMI women and Middle Eastern patients were
older and showed a higher prevalence of cardiovascular risk factors compared to MVD-AMI men and
South Asian patient population respectively. There were no significant differences recorded among the
different subgroups of MVD-AMI patients regarding the hospital outcome measures.
Conclusion: Our study highlighted the clinical characters and poor outcomes of a high-risk group of
MVD-AMI with different demographic backgrounds. Although age was a strong predictor for in-hospital
poor outcomes, neither gender nor ethnicity affected the outcomes in them.
artery disease (CAD) have more comorbidities and poor in-hospital outcomes. We aim to analyze MVDAMI
patients regarding clinical data and short-term outcomes.
Methods: This is a retrospective analysis of the prospectively collected data registry, a single-center study
reviewing the clinical details and hospital outcome measures of AMI patients referred to our center for
early revascularization from 2016 to 2019.
Result: Out of 3041 patients presented with AMI, 491 (16%) had MVD on coronary angiogram. MVD-AMI
patients were older, had a higher prevalence of DM, HTN, and prior history of ischemic heart disease
compared to the non- MVD -AMI group (p < 0.001 for all). However, they presented more with nonanterior
myocardial infarction, showed higher rates of post-myocardial infarction LV dysfunction, and
mortality (p < 0.001). Older MVD-AMI patients showed higher rates of in-hospital morbidities and
mortality compared to younger ones (p < 0.001). MVD- AMI women and Middle Eastern patients were
older and showed a higher prevalence of cardiovascular risk factors compared to MVD-AMI men and
South Asian patient population respectively. There were no significant differences recorded among the
different subgroups of MVD-AMI patients regarding the hospital outcome measures.
Conclusion: Our study highlighted the clinical characters and poor outcomes of a high-risk group of
MVD-AMI with different demographic backgrounds. Although age was a strong predictor for in-hospital
poor outcomes, neither gender nor ethnicity affected the outcomes in them.
Staff Members - Benha University