Background: To examine the value of speckle tracking echocardiography to detect the presence, extent
and severity of coronary artery affection in patients with suspected stable angina pectoris.
Methods: Two hundred candidates with suspected stable angina pectoris and normal resting
conventional echocardiography were subjected to speckle tracking echocardiography and coronary
angiography. Global and segmental longitudinal peak systolic strain were assessed and were correlated to
the results of coronary angiography for each patient.
Results: There was a statistically significant difference in the mean of global longitudinal peak systolic
strain between normal coronaries and different degrees of coronary artery disease (CAD) (
20.11
0.8
for normal,

18.34

2.52 for single vessel,

16.14

2.85 for two vessels,

14.81

2.12 for three vessels,

13.01

2.92 for left main disease). GLPSS showed high sensitivity for the diagnosis of single vessel CAD
(90%, specificity 95.1%, cutoff value:

18.44, AUC: 0.954); two vessels disease (90%, sensitivity 88.9%,
cutoff value

17.35, AUC: 0.906) and for three vessels CAD (cutoff value

15.33, sensitivity 63% and
specificity 72.2% AUC 0.681) segmental LPSS also showed statistical significance for localization of the
affected vessel for left anterior descending, left circumflex and right coronary artery (r = 0.001) and
inverse correlation with syntax score that was significant with high and intermediate score (r = 0.001)
and insignificant for low syntax score (r value 0.05).
Conclusion: Two-dimensional speckle tracking echocardiography has good sensitivity and specificity to
predict the presence, extent and severity of CAD.
© 2017 Published by Elsevier B.V. on behalf of Cardiological Society of India. This is an open access article
under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).