This work was carried out to study the inheritance of resistance to talcuiscase during the three successive seasons. 1989. 1990 and 1991. Two susceptible X resistant single crosses of maize each with six populations (P1. P2. F1. F2. B1. and B2) were tested for the disease under artificial infection lions. The following genetic parameters were estimated: Heterosis. ‘g depression. potence ratio. gene action, heritability in broad and ense. genetic advance upon selection and genetic coefficient of Th’ results could be summarized as follows: iiy significant negative heterosis and inbreeding depression values Dted for late wilt disease in both crosses indicating the importance of ve genetic variance in controlling this trait. Partial dominance of )ver susceptibility was detected in the two studied crosses. Most cr1ina test I were significant in both crosses. Uhe additive genetic variance was positive and highly significant. he highly significant value of dominance was of negative nature in both Significant estimates for two out of the three types of epistasis were For each cross. Generally. both additive and non-additive genetic re imnortailt in the inheritance of resistance to the disease. High heritability values in broad and narrow sense were obtained in the ses. The predicted genetic advance expressed s a percentage of the s high in both crosses