Efficacy of insecticides chlorpyrifos-methyl (CH), deltamethrin (DE) and spinosad (SP) was evaluated alone and
in binary combinations with carbon dioxide (CA) against Sitophilus oryzae (L.). Mortality of S. oryzae adults was
recorded after 3, 7 and 14 days, and progeny production and wheat weight loss were assessed after 90 days for all
treatments. In individual treatments, the mortality of S. oryzae adults was 69.5, 79.8, 50.7 and 61.4% after 14
days of exposure to the highest concentration of CA (30%), CH (0.5 mg/kg), DE (1.0 mg/kg) and SP (0.5 mg/kg),
respectively. Mortality of S. oryzae adults was higher in combined treatments at all tested rates than individual
treatments. Mortality of adults of 100% was obtained in combined treatments of CH (0.5 mg/kg) + CA (30%)
after 3 days and DE (1.0 mg/kg) + CA (30%) after 14 days of exposure. Combinations of SP + CA were more
effective than CH + CA and DE + CA as 100.0% mortality was achieved in combined treatments of SP at 0.25
mg/kg with CA at 20 and 30%, and SP at 0.5 mg/kg with CA at 20 and 30% after 3 days of exposure. Progeny
production of S. oryzae was decreased significantly in all treatments compared with untreated wheat grains after
90 days of exposure. High rates induced progeny reduction of 100% and complete protection of wheat grains
against damage caused by S. oryzae after 90 days. Moreover, germination percentages of wheat seeds treated
with CH at 0.5 mg/kg, DE at 1.0 mg/kg, CA at 30% and CH at 0.5 mg/kg + CA at 30% were 90.6, 86.7, 86.7 and
90.0, respectively. Our results indicate that the combination of insecticides with CA appears promising as an
approach for the control of S. oryzae.