Staff Members - Benha University
Saponins and their potential role in diabetes mellitus
Diabetes Manag. • 2017
Publication Information
Authors
AmiraRagab El Barky, Samy Ali Hussein, AbeerAbd-Elhameed AlmEldeen, yehia Ahmed Hafez & TarekMostafa Mohamed
Keywords
diabetes, medicinal plants, saponin, hyperglycaemia, sea cucumber
Journal
Diabetes Manag.
Publisher
Diabetes Management
Volume
7
Issue
1
Pages
148–158
publication.type
International
Paper Link
Open Link
Supplementary Materials
Not Available
Abstract
Diabetes Mellitus (DM) is a chronic metabolic disorder characterized by an increase in the
serum blood glucose levels. DM resulted from defects in insulin secretion, action, or both of
them. The chronic hyperglycemia resulted from diabetes can lead to irreversible damage,
dysfunction and failure of various organs. Glycosidic compounds namely, saponins, are
shown to have potential therapeutic benefits and are theorized as an alternative medication
in decreasing serum blood glucose level in patients they suffering from diabetes. This review
article aimed to elucidate the antidiabetic activity of saponins as well as showed their merit
that makes them ideal for antidiabetic remediation.
serum blood glucose levels. DM resulted from defects in insulin secretion, action, or both of
them. The chronic hyperglycemia resulted from diabetes can lead to irreversible damage,
dysfunction and failure of various organs. Glycosidic compounds namely, saponins, are
shown to have potential therapeutic benefits and are theorized as an alternative medication
in decreasing serum blood glucose level in patients they suffering from diabetes. This review
article aimed to elucidate the antidiabetic activity of saponins as well as showed their merit
that makes them ideal for antidiabetic remediation.