The present study was designed to evaluate the tolerance of enteral feeding in enterally-fed mechanically-ventilated patients during supine and prone positions as judged by measuring the residual gastric volume (RGV) and comprised 23 patients admitted to ICU. All patients were maintained on enteral feeding at a rate of 60 ml/ hour for 6 hours and immediately after the 6-hr period, RGV was determined and patient was turned to the other position and enteral feeding was continued for another 6 hours and at the end of which RGV was re-estimated. All patients were managed in both positions with head elevated for a maximum of 30o and the study was conducted in supine position first and then patients were turned to prone position. There was a non-significant increase in RGV in prone position compared to that estimated in supine position. Only 4 patients had RGV of >150 ml in both positions, while the other 19 patients had a mean RGV of