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A theoretical model for the delivery of magnetic nanoparticles through a blood vessel under the influence of a magnetic field

• 2021
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Publication Information
Authors SF Salem, VV Tuchin
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publication.type International
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Abstract
Magnetic nanoparticles, such as Superparamagnetic iron Oxide Nanoparticles (Fe3O4) are used in this theoretical study. These particles represent a unique nanoplatform with a great potential for the development of drug delivery systems via blood vessels, due to their biocompatibility and stability. The mechanisms of magnetic nanoparticles moving in Newtonian fluid (blood) in a static magnetic field are numerically studied. The equations of motion for particles in the flow are governed by a combination of magnetic equations for the permanent magnet field and the Navier-Stokes equations for fluid. These equations were solved numerically using the COMSOL Multiphysics Modeling Software.