Staff Members - Benha University
Comparison between Dexmedetomidine and Glyceryl Trinitrate in Improving Quality of the Operative Field During Functional Endoscopic Sinus Surgery
• 2022
Publication Information
Authors
Samer B. Kamela
, Ahmed S. Elkadya
, Mohsen M. Abd El-Razeka
, Mohammed H. Abd
El-Rahmanb
, Omar S. Abd Al Maksouda
Keywords
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Journal
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Publisher
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Volume
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Issue
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Pages
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publication.type
Local
Paper Link
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Supplementary Materials
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Abstract
Background: Functional endoscopic sinus surgery [FESS] is a wellestablished therapeutic option for intractable CRS. In case of major
bleeding, risk of complications such as meningitis, blindness,
intracranial injury, cerebrospinal fluid [CSF] leakage and the
duration of surgery increase. Aim of work: The present work aims to
compare between the efficacy of dexmedetomidine and glyceryl
trinitrate in inducing controlled hypotension to improve the quality of
the operative field during FESS under general anesthesia. Materials
and Methods: In our study, the number of patients was 40 which
were divided randomly into two groups: (a) Glyceryl trinitrate
group: twenty patients received Glyceryl trinitrate (GTN group).
(Dexmedetomidin group: twenty patients received Dexmedetomidine
(DEX group). Results: It was confirmed that dexmedetomidine
causes significant stable hemodynamics, excellent surgical field and
significant surgeon satisfaction compared to glyceryl trinitrate. It also
causes sedation effect so less extra doses of fentanyl were used.
Conclusion: We concluded that during ambulatory FESS, dexmedetomidine is more
effective than glyceryl trinitrate for providing controlled hypotension and rendering an
excellent surgical field with higher surgeon's satisfaction score and lesser analgesic
requirement without major hemodynamic alteration.
bleeding, risk of complications such as meningitis, blindness,
intracranial injury, cerebrospinal fluid [CSF] leakage and the
duration of surgery increase. Aim of work: The present work aims to
compare between the efficacy of dexmedetomidine and glyceryl
trinitrate in inducing controlled hypotension to improve the quality of
the operative field during FESS under general anesthesia. Materials
and Methods: In our study, the number of patients was 40 which
were divided randomly into two groups: (a) Glyceryl trinitrate
group: twenty patients received Glyceryl trinitrate (GTN group).
(Dexmedetomidin group: twenty patients received Dexmedetomidine
(DEX group). Results: It was confirmed that dexmedetomidine
causes significant stable hemodynamics, excellent surgical field and
significant surgeon satisfaction compared to glyceryl trinitrate. It also
causes sedation effect so less extra doses of fentanyl were used.
Conclusion: We concluded that during ambulatory FESS, dexmedetomidine is more
effective than glyceryl trinitrate for providing controlled hypotension and rendering an
excellent surgical field with higher surgeon's satisfaction score and lesser analgesic
requirement without major hemodynamic alteration.