أعضاء هيئة التدريس - جامعة بنها
Evaluation of Urinary and Serum Macrophage Migration Inhibition Factor in a group of Systemic Lupus Erythematosus Egyptian Patients
• 2022
معلومات البحث
المؤلفون
Mona E. Fouda a
, Ola S. El-shimi a
, Marwa Y. Mahgoub b
, Samar N. Abdelrahman a
, Amira MN
Abdelrahman
a
الكلمات المفتاحية
Not Available
المجلة العلمية
Not Available
الناشر
Not Available
المجلد
Not Available
العدد
Not Available
الصفحات
Not Available
publication.type
Local
رابط البحث
Not Available
المواد المرفقة
Not Available
الملخص
Objective: to evaluate the potential clinicopathological involvement
of macrophage migration inhibitory factor (MIF) in systemic lupus
erythematosus (SLE), and its relationship with lupus nephritis (LN)
through measuring serum and urinary MIF levels. Methods: A crosssectional case-control study was carried out on 30 SLE female
patients and 30 healthy age-matched females as a control group. SLE
activity was assessed by the Systemic Lupus Erythematosus Disease
Activity Index-2000 (SLEDAI-2k) and renal activity was evaluated
with the renal-SLEDAI (rSLEDAI-2k). SLE damage was evaluated
by the Systemic Lupus International Collaborating Clinics/American
College of Rheumatology (SLICC/ACR) damage index. Serum MIF
(sMIF), urinary MIF (uMIF) levels were assayed and
uMIF/creatinine ratio was estimated in all studied subjects. Results:
SLE patients had significantly higher levels of sMIF, uMIF and
uMIF/ creatinine ratio than the control group (p
of macrophage migration inhibitory factor (MIF) in systemic lupus
erythematosus (SLE), and its relationship with lupus nephritis (LN)
through measuring serum and urinary MIF levels. Methods: A crosssectional case-control study was carried out on 30 SLE female
patients and 30 healthy age-matched females as a control group. SLE
activity was assessed by the Systemic Lupus Erythematosus Disease
Activity Index-2000 (SLEDAI-2k) and renal activity was evaluated
with the renal-SLEDAI (rSLEDAI-2k). SLE damage was evaluated
by the Systemic Lupus International Collaborating Clinics/American
College of Rheumatology (SLICC/ACR) damage index. Serum MIF
(sMIF), urinary MIF (uMIF) levels were assayed and
uMIF/creatinine ratio was estimated in all studied subjects. Results:
SLE patients had significantly higher levels of sMIF, uMIF and
uMIF/ creatinine ratio than the control group (p