Background: Vaginal atrophy (VA) is changing of vagina and developing when estrogen significantly
decreased. Aim: Was to evaluate the nursing teaching guideline on improving knowledge and attitude among menopausal
women's regarding vaginal atrophy. Research Design: A Quasi experimental, one group study design utilized. Setting:
Administrative building at Ain-Shams University. Sampling: 116 sample of menopausal women according to inclusion
criteria. Tools: A structured interviewing questionnaire, assessment of women's knowledge regarding menopause and VA
and assessment of women's attitude regarding vaginal atrophy. Results: Minority of the studied women (12.6%) had good
knowledge regarding menopause and VA pre intervention which increased to (58.0%) post intervention, However more than
two thirds of the studied women (68.1 %) had positive attitude regarding VA pre intervention which increased to (79.8%)
post intervention. Additionally, there were statistical significant relation between total knowledge score and total attitude
score pre intervention, while there were no statistical significant relation post interventions. Conclusion: There were
statistical significant relationship between total knowledge and total attitude score pre intervention, in contrast, no statistical
relationship in post intervention. There was significant improving in women's knowledge and attitude regarding vaginal
atrophy. Therefore, our hypothesis was approved. Recommendations: encourage healthy and positive attitude about VA in
women in early age rather than teaching them when grown up.